Antimosquito and antimicrobial clerodanoids and a chlorobenzenoid from Tessmannia species

Publication Type

Journal Article

Journal Name

Natural Product Communications

Publication Date

1-1-2010

Abstract

The clerodane diterpenoids trans-kolavenolic acid, 18-oxocleroda-3,13(E)- dien-15-oic acid, ent-(18-hydroxycarbonyl)-cleroda-3,13(E)-dien-15-oate, 2-oxo-ent-cleroda-3,13(Z)-dien-15-oic acid and trans-2-oxo-ent-cleroda-13(Z)-en- 15-oic acid, and the chlorobenzenoid O-(3-hydroxy-4-hydroxycarbonyl-5- pentylphenyl)-3-chloro-4-methoxy-6-pentyl-2-oxybenzoic acid were isolated from Tessmannia martiniana var pauloi and T. martiniana var matiniana. Structures were established based on interpretation of spectroscopic data. Some of the compounds exhibited significant antimosquito, antifungal and antibacterial activities.

Keywords

Anti-mosquitoes, Antimicrobials, Caesalpiniaceae, Chlorobenzenoid, ent-clerodanoids, T. Martiniana var martiniana, Tessmannia martiniana var pauloi

PubMed ID

20334122

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