Effect of anti-thymocyte serum on acquisition of resistance to infestation by Rhipicephalus appendiculatus larvae in rabbits

Publication Type

Journal Article

Journal Name

Onderstepoort Journal of Veterinary Research

Publication Date

1-1-1996

Abstract

Administration of specific goat anti-thymocyte serum (ATS) to rabbits, prior to a primary infestation by Rhipicephalus appendiculatus larvae, blocked the acquisition of resistance significantly only in the third infestation. The larvae which fed on these rabbits had higher engorgement masses than did those feeding on untreated control rabbits. Also, a higher percentage (92%) of larval ticks fed on these animals than on the controls (88%). ATS also induced a leucopenia due to a lymphopenia in the treated rabbits. It was concluded that a T-cell-dependent component might be involved in acquired resistance to infestation by R. appendiculatus.

Keywords

Anti-thymocyte serum, ATS, Rabbits, Resistance to infestation, Rhipicephalus appendiculatus

PubMed ID

8917858

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