Publication Type

Journal Article

Journal Name

Veterinary Research Communications

Publication Date

12-1-1984

Abstract

The homologous skin sensitizing activity of serum from tick-naive cattle (Bos taurus) and from cattle resistant to the tick Rhipicephalus appendiculatus was tested by attempting to induce passive cutaneous anaphylaxis (PCA) in ticknaive calves. The serum from tick-resistant cattle induced PCA, whereas that from tick-naive cattle failed to do so. The PCA was more marked at 72 hours than at 24 hours after administration of the serum. Treatment of the serum by heat at 56°C for 2 hours or by adding 0.1 M 2-mercaptoethanol to it reduced its ability to sensitize. Serum from tick-resistant cattle did not sensitize the skin of heterologous species, namely rabbits, guinea-pigs and rats. © 1984 Elsevier Science Publishers B.V.

PubMed ID

6516209

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